Govt Study Proves THC From Cannabis Destroys Leukemia, Breast And Lung Cancer Cells

Posted by on Oct 30, 2011 in Cancer, Cannabinoids, Cannabis, Cannabis Oil, Disease, Healing, Health, Science20 comments

Is lipid signaling through cannabinoid 2 receptors part of a protective system?

Pacher P, Mechoulam R.

Source

Laboratory of Physiologic Studies, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD 20892-9413, USA. Pacher@mail.nih.gov

Abstract

The mammalian body has a highly developed immune system which guards against continuous invading protein attacks and aims at preventing, attenuating or repairing the inflicted damage. It is conceivable that through evolution analogous biological protective systems have been evolved against non-protein attacks. There is emerging evidence that lipid endocannabinoid signaling through cannabinoid 2 (CB₂) receptors may represent an example/part of such a protective system/armamentarium. Inflammation/tissue injury triggers rapid elevations in local endocannabinoid levels, which in turn regulate signaling responses in immune and other cells modulating their critical functions. Changes in endocannabinoid levels and/or CB₂ receptor expressions have been reported in almost all diseases affecting humans, ranging from cardiovascular, gastrointestinal, liver, kidney, neurodegenerative, psychiatric, bone, skin, autoimmune, lung disorders to pain and cancer, and modulating CB₂ receptor activity holds tremendous therapeutic potential in these pathologies. While CB₂ receptor activation in general mediates immunosuppressive effects, which limit inflammation and associated tissue injury in large number of pathological conditions, in some disease states activation of the CB₂ receptor may enhance or even trigger tissue damage, which will also be discussed alongside the protective actions of the CB₂ receptor stimulation with endocannabinoids or synthetic agonists, and the possible biological mechanisms involved in these effects.

Published by Elsevier Ltd.

PMID:
21295074
[PubMed - indexed for MEDLINE]
PMCID: PMC3062638
[Available on 2012/4/1]
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20 comments

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  1. Thank you, I really thank you for knowledge on this one. Have a great day and I look forward to returning.

  2. splendide article , merci pour le reseignement

  3. Wow wish the government in australia would take notice of this artical…My father use’s for medical reason’s and with all the research we have done on the plant and it’s benifit’s they should take note…my father has cancer and he’s not willing to try the chemo but was and is still willing to use the cannabis for that exact reasoning..

  4. Funny how no matter what information we go to the Government with, they still won’t listen. Because as Harper of Canada says “Drugs are bad because they are Illegal, they are illegal because they are bad. Now Harper, I would like to ask you to back up your information with proof!!!! Because there is none!! Ya, that’s right!
    It’s sad that our country is willing to kill millions of people, and send millions to jails just to sit on the fact that “it’s illegal because it’s bad”. If that is the case, then PROVE IT!!!

  5. where can i find acual stats of the study?

  6. Darn. Is the full study publicly published anywhere? The abstract says it’s not available to the public until next April. I’d be interested to see if the rest of it might mention these cancers and indicate proof that it destroys cancer cells. This would be amazing and provide a little hope for many people! This abstract only says that in some cases it helped produce anti-inflammatory response which prevented associated tissue damage; but it also said in some diseases it may actually enhance or even CAUSE tissue damage. It also says “it is conceivable that … protective systems have been evolved against non-protein attacks.” Maybe this is where this study illustrates cancer-killing properties?

  7. Two words..Legalize it… I don’t Big Pharma..it’s a plant; easy to grow..God given and NOBODY has the right to stop people from benefiting from it.

  8. sorry, correction: I don’t need Big Pharma to grow it or process it nor make money from it…just legalize it.
    It is a God-given plant and man doesn’t have the right to control this, not only basically harmless, but in fact truly helpful plant.
    Suz
    I wish people would grow up and see the light about this.

  9. Time to go smoke some weed (Y)

  10. [...] dis shit? "GOV'T Study Proves THC Destroys Cancer Cells" http://www.bayareacannabis.org/?p=311 Govt Study Proves THC From Cannabis Destroys Leukemia, Breast And Lung Cancer Cells Posted by [...]

  11. Its all about power and control. The people with power want full control of the common people. As long as they control, they have power. Thats why drugs will never be legal.

  12. If my criminal activities could also save my life then I’ll be a criminal till the day I die. If the government wants to put me down for it then they are demeaning themselves in my eyes.

  13. Just read the article. NO WHERE does it say that it can destroy specifically Leukemia, breast, and lung cancer cells… I offer an exerpt that sums it nicely.

    “The levels of CB2 receptor and its endogenous ligand 2-AG are elevated in endometrial carcinoma [210] and CB2 receptors are also expressed on malignancies of the immune system [209]. In immune cancer cells CB2 stimulation triggered apoptosis, suggesting that selective CB2 ligands may serve as novel anticancer agents to selectively target and kill tumors of immune origin [209].

    As the above mentioned examples clearly illustrate that the situation regarding the role of the endocannabinoid system in cancer is very complicated and may largely depend on the tumor type, expression of cannabinoid receptors in the tumor, tumor microenvironment, and several other factors.”

    Please don’t generalize the results and sensationalize this. It’s not only bad journalism, it just makes you look like an idiot. :\

    I will say though that I am pleased with the results themselves. They are so close in finding a way of using this information to locate and target cancer cells. Maybe the politicians and such will shut up about it…

  14. Cannabis is taking longer to be legalized because of stoners who say stupid stuff like “yeah man weed is a plant which means its good and totally natural and good for you”, or who (purposefully?) misinterpret scientific studies and use words like “prove”. From reading the abstract, this study didn’t show anything like killing cancer cells. In fact, the abstract doesn’t even really demonstrate any results other than to say that they were mixed and in some cases it may help inflammation, in some cases it may make it worse.

    1. Scientific studies don’t “prove” anything, get your terminology right.
    2. Unless you have access to the full document and know something not mentioned in the abstract, you’re wrong with your title.
    3. It’s just giving more ammunition to the opposition if you keep peddling false information, and makes you no better than the DARE bullshit that we know and hate.

    In sum, spread the truth, not bullcrap feel-good hippie stoner rhetoric.

  15. The article will not go public until April so our wonderful leaders can change it around to suit their needs and desires like they do every single other fact for furthering their agendas of erroding freedoms. I love to go on. . . . .

  16. Wow annoyed smoker….couldn’t have said it better myself..

  17. I want to see the complete study. This is just an abstract which doesn’t even summarize it ‘all’ just a reasoning of what the study is for.

    Anyone know where to find the complete actual study? I’d love to be able to read it further. I did all my college papers on medicinal uses of marijuana and I find the area very interesting.

  18. awesome article!!! I’ll mos definately share with my network :)

  19. my opion about weed and the so many reasons anyone smokes it is not that they smoke for the party they smoke to get well. It’s when the younger generation start asking them of thier “high” thats what makes weed sound bad and it makes the ill person feel like their doing something real bad, yes guilt sets in and then the feeling of police and getting caught, everything. I think just because the younger generation uses it like we did in the 60s now is the reason it’s still illigial. Some of us dont have the money for the doctor or the script and they are the one police target..I know first hand, i’m sick and a victim..

  20. If you think this is about smoking Cannabis you are mistaken. It’s referring to the ingestion of the oil. I know smoking helps ease but the oils cures a great deal. I work with patients through America and some do not make it but the ones that turn everything about the life style around generally pull out. You can not medicate yourself out of an illness you walked yourself into. A life awakening has to take place and changes throughout it must take place. The oil will oil help reinforce your Endocannabinoid system and bring a balance for healing. It’s up to you to stop the causation of that illness.