Cannabidiol Displays Antiepileptiform and Antiseizure Properties In Vitro and In Vivo
Nicholas A. Jones, Andrew J. Hill, Imogen Smith, Sarah A. Bevan, Claire M. Williams, Benjamin J. Whalley and Gary J. Stephens + Author Affiliations School of Pharmacy (N.A.J., A.J.H., I.S., S.A.B., B.J.W., G.J.S.) and School of Psychology (N.A.J., A.J.H., C.M.W.), University of Reading, Whiteknights, Reading, United Kingdom Address correspondence to: Dr. Gary Stephens, School of [...]
Cannabindiol
CBD (cannabidiol) – Cannabidiol is the cannabinoid obtaining most recent mainstream exposure for its multitude of benefits with non-psychoactive effects. Unites States Patent #6,630,507 – Hampson, et al. found cannabinoids (specifically CBD) effective as antioxidants & neuroprotectants without providing any psychoactive effects. Neuroprotective antioxidant more potent than ascorbate or topopherol with ability to pass the [...]
Similar Readily Cannabinoids Penetrate into the Brain
The pharmacokinetics (behaviour of a substance in the body) of cannabidiol (CBD), cannabidivarine (CBDV), delta-9- tetrahydrocannabivarin (delta-9-THCV) and cannabigerol (CBG) in mice and rats were investigated at the University of Aberdeen, UK. Researchers determined concentrations in the brain after intraperitoneal (injection into the abdomen) and oral administration. The effects of CBD were further investigated in [...]
Cannabindiol Crosses the Blood Brain Barrier
11/08/08 Dr. Courtney speaks on the CANNABIS ISSUES PANEL of experts and authors at the 18th ANNUAL SOUTHERN HUMBOLDT HEMP FEST Emcee: Jimmy Durchslag: Next we have William Courtney, DR. BILL COURTNEY, Cannabis Medical Consultant. Many of you… I know he’s based in Mendocino, has an office in Willits, but he’s also here in our [...]
Anti-Inflammatory Role of Cannabidiol helps in Induced Acute Pancreatitis in Mice.
Source From the *Institute of Digestive Disease, Department of Pathophysiology, Tongji University School of Medicine, Shanghai, China; and †Department of Internal Medicine II, Klinikum Grosshadern, Ludwig Maximilians University, Munich, Germany. Abstract OBJECTIVES: The anti-inflammatory effects of O-1602 and cannabidiol (CBD), the ligands of G protein-coupled receptor 55 (GPR55), on experimental acute pancreatitis (AP) were investigated. [...]
