German scientists from the universities of Goettingen, Hamburg
and Dresden reported of the treatment of a 15-year-old boy with
treatment refractory Tourette Syndrome (TS) and attention deficit
hyperactivity disorder (ADHD) leading to severe physical and
psychosocial impairment. Administration of THC resulted in a
considerable improvement of tics without adverse effects,
allowing parallel stimulant treatment of comorbid ADHD. Along
with THC treatment, intracortical inhibition, that is inhibition of
signal transmission between nerve cells in the cortex of the brain,
was increased.

Authors concluded that "our observation suggests that delta-9-
THC might be a successful alternative in patients with severe TS
refractory to classic treatment. Particularly in the case of
stimulant-induced exacerbation of tics, delta-9-THC might enable
successful treatment of comorbid ADHD. The enhancement of
intracortical inhibition might be mediated by modulating release of
several neurotransmitters including dopamine and gamma-
aminobutyric acid."

(Source: Hasan A, Rothenberger A, Münchau A, Wobrock T,
Falkai P, Roessner V. Oral delta9-tetrahydrocannabinol improved
refractory gilles de la tourette syndrome in an adolescent by
increasing intracortical inhibition: a case report. J Clin
Psychopharmacol 2010;30(2):190-2.)
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Arthur Livermore
National Director
American Alliance for Medical Cannabis
44500 Tide Avenue
Arch Cape, OR 97102 USA
Phone: 503-436-1882
Email: national.director@letfreedomgrow.com