Cannabidiol Displays Antiepileptiform and Antiseizure Properties In Vitro and In Vivo

By | Aug 24, 2012

Nicholas A. Jones, Andrew J. Hill, Imogen Smith, Sarah A. Bevan, Claire M. Williams, Benjamin J. Whalley and Gary J. Stephens + Author Affiliations School of Pharmacy (N.A.J., A.J.H., I.S., S.A.B., B.J.W., G.J.S.) and School of Psychology (N.A.J., A.J.H., C.M.W.), University of Reading, Whiteknights, Reading, United Kingdom Address correspondence to: Dr. Gary Stephens, School of [...]

Cannabindiol

By | Aug 24, 2012

CBD (cannabidiol) – Cannabidiol is the cannabinoid obtaining most recent mainstream exposure for its multitude of benefits with non-psychoactive effects. Unites States Patent #6,630,507 – Hampson, et al. found cannabinoids (specifically CBD) effective as antioxidants & neuroprotectants without providing any psychoactive effects. Neuroprotective antioxidant more potent than ascorbate or topopherol with ability to pass the [...]

Similar Readily Cannabinoids Penetrate into the Brain

By | Aug 24, 2012

The pharmacokinetics (behaviour of a substance in the body) of cannabidiol (CBD), cannabidivarine (CBDV), delta-9- tetrahydrocannabivarin (delta-9-THCV) and cannabigerol (CBG) in mice and rats were investigated at the University of Aberdeen, UK. Researchers determined concentrations in the brain after intraperitoneal (injection into the abdomen) and oral administration. The effects of CBD were further investigated in [...]

Cannabindiol Crosses the Blood Brain Barrier

By | Aug 24, 2012

11/08/08 Dr. Courtney speaks on the CANNABIS ISSUES PANEL of experts and authors at the 18th ANNUAL SOUTHERN HUMBOLDT HEMP FEST Emcee: Jimmy Durchslag: Next we have William Courtney, DR. BILL COURTNEY, Cannabis Medical Consultant. Many of you… I know he’s based in Mendocino, has an office in Willits, but he’s also here in our [...]

The Human Endocannabinoid System

By | Jun 18, 2012

The Endocannabinoid System (ECS) started revealing itself to researchers in the 1940s and by the late ‘60s the basic structure and functionality had been laid out. Today we know the ECS is a comprehensive system of biochemical modulators that maintain homeostasis in all body systems including the central and peripheral nervous systems, all organ systems, [...]

THC and Cannabinol Activate Capsaicin-Sensitive Sensory Nerves via a CB1 and CB2 Cannabinoid Receptor-Independent Mechanism

By | Jun 18, 2012

Peter M. Zygmunt, David A. Andersson, and Edward D. Högestätt + Author Affiliations 1 Department of Clinical Pharmacology, Institute of Laboratory Medicine, Lund University Hospital, SE-221 85 Lund, Sweden  Abstract Although Δ9-tetrahydrocannabinol (THC) produces analgesia, its effects on nociceptive primary afferents are unknown. These neurons participate not only in pain signaling but also in the [...]

Science/Human: Synthetic cannabinoid improves survival after severe brain injury in clinical study

By | Jun 18, 2012

In a clinical study with 97 comatose patients a synthetic cannabinoid (named KN38-7271) improved survival in the acute early phase after a head injury. The trial was conducted in 14 EURopean neurosurgical centres. KN38-7271 binds both to the CB1 and the CB2 receptor, similar to THC and some other cannabinoids. Participants received 1 or 0.5 mg [...]

Cancer & Fungus or Why Cannabis’ anti-fungal properties may be working on Cancers.

By | Apr 19, 2012

Cancer is a fungus, can be caused by a fungus, or is accompanied by late-stage fungal infections, and now the Mayo Clinic confirms this. They are not the first to say so though. Many, even from the official world of orthodox oncology, recognize the similarities of cancer and fungal infections, the decay that ties these [...]

Marijuana-Like Chemicals Inhibit Human Immunodeficiency Virus (HIV) in Late-State AIDS

By | Mar 25, 2012

Medical marijuana is prescribed to treat pain, debilitating weight loss and appetite suppression, side effects that are common in advanced AIDS. This is the first study to reveal how the marijuana receptors found on immune cells — called cannabinoid receptors CB1 and CB2 — can influence the spread of the virus. Understanding the effect of [...]

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