Endocannabinoid signaling in the amygdala: anatomy, synaptic signaling, behavior, and adaptations to stress.

By | Aug 28, 2012

The molecular constituents of endocannabinoid (eCB) signaling are abundantly expressed within the mammalian amygdaloid complex, consistent with the robust role of eCB signaling in the modulation of emotional behavior, learning, and stress-response physiology. Here, we detail the anatomical distribution of eCB signaling machinery in the amygdala and the role of this system in the modulation [...]

Anti-Inflammatory Role of Cannabidiol helps in Induced Acute Pancreatitis in Mice.

By | Aug 12, 2012

Source From the *Institute of Digestive Disease, Department of Pathophysiology, Tongji University School of Medicine, Shanghai, China; and †Department of Internal Medicine II, Klinikum Grosshadern, Ludwig Maximilians University, Munich, Germany. Abstract OBJECTIVES: The anti-inflammatory effects of O-1602 and cannabidiol (CBD), the ligands of G protein-coupled receptor 55 (GPR55), on experimental acute pancreatitis (AP) were investigated. [...]

The Human Endocannabinoid System

By | Jun 18, 2012

The Endocannabinoid System (ECS) started revealing itself to researchers in the 1940s and by the late ‘60s the basic structure and functionality had been laid out. Today we know the ECS is a comprehensive system of biochemical modulators that maintain homeostasis in all body systems including the central and peripheral nervous systems, all organ systems, [...]

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