Cannabinoids

Cannabinoids that are produced in our bodies help regulate every single system in our bodies: our nervous system, our digestive system, our reproductive system, our immunological system, our endocrine system, and every other system. Cannabinoids are the essential ingredient involved in maintaining what’s known as homeostatic balance. Imagine balancing a pencil on your finger with 100 things on each side trying to move around. Add this all up and you have what they call your Endocannabinoid system. A super computer has nothing on it.

Unfortunately there are many people who are not making enough Cannabinoids or their system is not active enough to benefit from the existing Cannabinoids in their system. There are millions of people whose body is not regulating all of the essential cannabinoids. Cannabinoid deficiency begins and the pencil is starting to move around. Bad thing.

A CBD-based health program needs to start being looked at to find the balance that’s required for our optimum health.  We have found forms of Cannabis oil can help, if not ensure this balance of Cannabinoids is achieved in your system!

The History of Cannabinoids

The cannabinoid system first appeared 6000 years ago. Our bodies produce Cannabinoid compounds to make us hungry . When enough food has been consumed we turn off those compounds and our desire for food goes away.  Food and feeding is at the heart of evolution and the development of new species, and Cannabinoids have evolved to regulate this system and every other system in our body. The Endocannabinoid system was only discovered in 1996 (so it’s reported). This restricted the understanding of how Cannabis could have any relationship with the human body. It seems that the Cannabis plant’s Photocannabinoids match most those of all mammals. Now that we do have this medical information, it’s making more and more sense just how powerful this knowledge really is. As a matter of fact, it’s believed that if this information went main stream, There are many, very rich people, that would take a huge loss. This may bring to light why there has been so much money spend to hide the true facts about the plants Photocannabinoids medicinal properties. In fact, CBD, Cannabidiol has been patented by the American Government.

What is a Plant Cannabinoids?

The term Cannabinoids or more correctly, Photocannabinoids, refers to a unique group of secondary metabolites found in the cannabis plant. These are responsible for the plant’s highly effective pharmacological effects.  Many feel that these Cannabinoids that heal our immune system are a group of substances that are related to Tetrahydrocannabinol (THC) and that bind to cannabinoid receptors. This statement is the main mindset that is thought of when we think about Cannabis. But as with our body’s complexity, so is the Cannabis plant’s system. Currently there are 4 main Cannabinoids being talked about. THC of course but picking up a lot of recent headlines is the CBD or Cannabidiol. It appears CBD’s fortify our immunity system by being absorbed additional amounts of CBD Cannabinoids While THC is getting all the hype, the CBD is quietly working away in the background. Like that step-mom you always hear about cleaning your house and into everyone’s business. THC appears to be working it’s best in the upper regions of the body. It’s excellent for head inflictions and disease, including tumors.  High levels of CBD’s helps block the upper CB1 receptors and redirects THC to follow along with the other Cannabinoids being introduced to receptors that occur naturally in the nervous and immune systems.  There are currently two known cannabinoid receptor subtypes termed CB1 and CB2. The CB1 receptor is expressed mainly in the brain (central nervous system, CNS), but also in the lungs, liver and kidneys. The CB2 receptor is mainly expressed in the immune system and in hematopoietic cells.

Cannabinoid receptor type 1

CB1 receptors are found primarily in the brain, specifically in the basal ganglia and in the limbic system, including the hippocampus. They are also found in the cerebellum and in both male and female reproductive systems. CB1 receptors appear to be responsible for the euphoric and anticonvulsive effects of cannabis.

CB1 receptors are essentially absent in the medulla oblongata, the part of the brain stem that is responsible for respiratory and cardiovascular functions. Thus, there is not a risk of respiratory or cardiovascular failure as there is with many other drugs.

Cannabinoid receptor type 2

CB2 receptors are almost exclusively found in the immune system, with the greatest density in the spleen. Generally found only in the peripheral nervous system, CB2 receptors appear to be responsible for the anti-inflammatory and possibly other therapeutic effects of cannabis.

Cannabinoids and Cannabinoid Receptors Evolving Together

Can one argue that this is occurring between cannabis and humans? Certainly, the partnership has been good for cannabis. Once confined to central Asia, cannabis has been distributed by humans to all four corners of the globe. Different cannabis species have developed due to human selection for industrial, nutritional or medicinal traits. Cannabis has become a stronger, more diverse, more adaptive and more widely-cultivated plant as a result of it’s relationship with us.

Reference 2

Reference 1:

Matsuda LA, Lolait SJ, Brownstein MJ, Young AC, Bonner TI (1990). “Structure of a cannabinoid receptor and functional expression of the cloned cDNA”. Nature 346 (6284): 561–4. doi:10.1038/346561a0. PMID 2165569.

Gérard CM, Mollereau C, Vassart G, Parmentier M (1991). “Molecular cloning of a human cannabinoid receptor which is also expressed in testis”. Biochem. J. 279 ( Pt 1): 129–34. PMID 1718258. PMC 1151556. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pubmed&pubmedid=1718258.


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